Interferon-Lambda 1 Inhibits Staphylococcus aureus Colonization in Human Primary Keratinocytes

Methicillin-Resistant Staphylococcus aureus Adaptation to Human Keratinocytes

UNLABELLED Skin is the most common site of Staphylococcus aureus infection. While most of these infections are self-limited, recurrent infections are common. Keratinocytes and recruited immune cells participate in skin defense against infection. We postulated that S. aureus is able to adapt to the milieu within human keratinocytes to avoid keratinocyte-mediated clearance. From a collection of S...

Interferon Lambda Inhibits HIV-1 Infection of Macrophages

Staphylococcus aureus Colonization in Atopic Skin Diseases

An epidemiologic investigation on Staphylococcus aureus (S. aureus) colonization in atopic skin diseases ZDV FRQGXFWHG DW øQ|Q 8QLYHUVLW\ 7XUJXW g]DO 0HGLFDO &HQWHU 7KH LQFLGHQFH RI XQDIIHFWHG VNLQ OHVLRQDO skin, and nasal positivity for S. aureus was examined in a total of 60 patients with atopic dermatitis and other atopic skin diseases. 50 healthy subjects were studied as controls. Normal s...

Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection.

UNLABELLED Much of the morbidity and mortality associated with influenza virus respiratory infection is due to bacterial coinfection with pathogens that colonize the upper respiratory tract such as methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae. A major component of the immune response to influenza virus is the production of type I and III interferons. Here we s...

Antibiotics, acne, and Staphylococcus aureus colonization.

OBJECTIVES To determine the frequency of Staphylococcus aureus colonization among patients with acne and to compare the susceptibility patterns between the patients who are using antibiotics and those who are not using antibiotics. DESIGN Survey (cross-sectional) study of patients treated for acne. SETTING Dermatology outpatient office practice PARTICIPANTS The study included 83 patients ...